Acs Medicinal Chemistry Letters

Journal Title：Acs Medicinal Chemistry Letters

ACS Medicinal Chemistry Letters is interested in receiving manuscripts that discuss various aspects of medicinal chemistry. The journal will publish studies that pertain to a broad range of subject matter, including compound design and optimization, biological evaluation, drug delivery, imaging agents, and pharmacology of both small and large bioactive molecules. Specific areas include but are not limited to:

Identification, synthesis, and optimization of lead biologically active molecules and drugs (small molecules and biologics)

Biological characterization of new molecular entities in the context of drug discovery

Computational, cheminformatics, and structural studies for the identification or SAR analysis of bioactive molecules, ligands and their targets, etc.

Novel and improved methodologies, including radiation biochemistry, with broad application to medicinal chemistry

Discovery technologies for biologically active molecules from both synthetic and natural (plant and other) sources

Pharmacokinetic/pharmacodynamic studies that address mechanisms underlying drug disposition and response

Pharmacogenetic and pharmacogenomic studies used to enhance drug design and the translation of medicinal chemistry into the clinic

Mechanistic drug metabolism and regulation of metabolic enzyme gene expression

Chemistry patents relevant to the medicinal chemistry field.

ACS 药物化学快报欢迎收录讨论药物化学各个方面的稿件。该期刊将发表涉及广泛主题的研究，包括化合物设计和优化、生物评估、药物输送、成像剂以及小分子和大分子生物活性分子的药理学。具体领域包括但不限于：

先导生物活性分子和药物（小分子和生物制剂）的鉴定、合成和优化

药物发现背景下新分子实体的生物学表征

用于鉴定或 SAR 分析生物活性分子、配体及其靶标等的计算、化学信息学和结构研究。

新颖和改进的方法，包括辐射生物化学，广泛应用于药物化学

从合成和天然（植物和其他）来源发现生物活性分子的技术

解决药物处置和反应机制的药代动力学/药效学研究

用于增强药物设计和将药物化学转化为临床的药物遗传学和药物基因组学研究

药物代谢机制和代谢酶基因的调控表达

与药物化学领域相关的化学专利。

Acs Medicinal Chemistry Letters创刊于2010年，由American Chemical Society出版商出版，收稿方向涵盖CHEMISTRY, MEDICINAL全领域，此刊是中等级别的SCI期刊，所以过审相对来讲不是特别难，但是该刊专业认可度不错，仍然是一本值得选择的SCI期刊 。平均审稿速度 一般,3-8周 ，影响因子指数3.5，该期刊近期没有被列入国际期刊预警名单，广大学者值得一试。