Toxicology In Vitro

Journal Title：Toxicology In Vitro

Toxicology in Vitro publishes original research papers and reviews on the application and use of in vitro systems for assessing or predicting the toxic effects of chemicals and elucidating their mechanisms of action. These in vitro techniques include utilizing cell or tissue cultures, isolated cells, tissue slices, subcellular fractions, transgenic cell cultures, and cells from transgenic organisms, as well as in silico modelling. The Journal will focus on investigations that involve the development and validation of new in vitro methods, e.g. for prediction of toxic effects based on traditional and in silico modelling; on the use of methods in high-throughput toxicology and pharmacology; elucidation of mechanisms of toxic action; the application of genomics, transcriptomics and proteomics in toxicology, as well as on comparative studies that characterise the relationship between in vitro and in vivo findings. The Journal strongly encourages the submission of manuscripts that focus on the development of in vitro methods, their practical applications and regulatory use (e.g. in the areas of food components cosmetics, pharmaceuticals, pesticides, and industrial chemicals). Toxicology in Vitro discourages papers that record reporting on toxicological effects from materials, such as plant extracts or herbal medicines, that have not been chemically characterized.

《体外毒理学》发表原创研究论文和评论，内容涉及体外系统在评估或预测化学物质毒性作用和阐明其作用机制方面的应用和使用。这些体外技术包括利用细胞或组织培养物、分离细胞、组织切片、亚细胞部分、转基因细胞培养物和转基因生物细胞以及计算机模拟。该期刊将重点关注涉及开发和验证新体外方法的研究，例如基于传统和计算机模拟预测毒性作用；高通量毒理学和药理学方法的使用；毒性作用机制的阐明；基因组学、转录组学和蛋白质组学在毒理学中的应用，以及描述体外和体内发现之间关系的比较研究。本期刊强烈鼓励投稿关注体外方法的开发、其实际应用和监管用途（例如在食品成分化妆品、药品、农药和工业化学品领域）。《体外毒理学》不鼓励投稿记录未经化学鉴定的材料（如植物提取物或草药）的毒理学效应报告的论文。

Toxicology In Vitro创刊于1987年，由Elsevier Ltd出版商出版，收稿方向涵盖医学 - 毒理学全领域，此刊是中等级别的SCI期刊，所以过审相对来讲不是特别难，但是该刊专业认可度不错，仍然是一本值得选择的SCI期刊 。平均审稿速度 约2.0个月 约10.9周，影响因子指数2.6，该期刊近期没有被列入国际期刊预警名单，广大学者值得一试。